The Maudsley environmental risk score for psychosis

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Environmental risk factors for psychosis

Genetic factors are clearly important in the etiology of schizophrenia, but the environment in which an individual's genes find expression is also crucial to the development of the illness. In this review of environmental risk factors for schizophrenia, we consider risks operating prenatally and perinatally, during childhood, and then later in life prior to illness onset Some of these risk fact...

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Henry Maudsley on Swedenborg's messianic psychosis.

BACKGROUND Creativity, religiosity and madness have long been thought to be aetiologically interrelated. METHOD Henry Maudsley's little known pathography of the 17th century Swedish philosopher and polymath, Emanuel Swedenborg, was examined. RESULTS Swedenborg developed a messianic psychosis in middle life, considered by Maudsley to be a monomania, possibly due to epilepsy. Many of Swedenbo...

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The "polyenviromic risk score": Aggregating environmental risk factors predicts conversion to psychosis in familial high-risk subjects.

BACKGROUND Young relatives of individuals with schizophrenia (i.e. youth at familial high-risk, FHR) are at increased risk of developing psychotic disorders, and show higher rates of psychiatric symptoms, cognitive and neurobiological abnormalities than non-relatives. It is not known whether overall exposure to environmental risk factors increases risk of conversion to psychosis in FHR subjects...

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ژورنال

عنوان ژورنال: Psychological Medicine

سال: 2019

ISSN: 0033-2917,1469-8978

DOI: 10.1017/s0033291719002319